OraMD Research


Latest Research: A study was recently conducted by University of Kentucky’s Center for Oral Health Research, in Lexington, KY USA. The study was to test the antibacterial effects of OraMD’s essential oils on oral pathogens. The study’s conclusion states: “The composite mixture of peppermint, spearmint, and almond oils has effective antibacterial activity…” Click below to view the full published study:



After researching oral problems for the better part of a decade, it became clear that only 22 types of bacteria cause most of the common issues such as gum disease, periodontal disease, bleeding gums, bad breath, receding gums and a host of others. The 3 specific species of all-natural botanical oils we discuss below create the perfect antidote to control the 22 types of bacteria and effectively let your mouth heal itself. OraMD consists of peppermint, spearmint, and almond oils, perfectly formulated for best results. Below is a snapshot look at exactly what each ingredient does in your quest to oral success.



Peppermint, Spearmint – fungi inhibition properties

The experiment below shows the effectiveness of peppermint and spearmint in 4 bacteria naturally found in the human mouth.


Essential oils of 12 medicinal plants were tested for inhibitory activity against Aspergillus flavus, A. parasiticus, A. ochraceus and Fusarium moniliforme. The oils of thyme and cinnamon 500 ppm, marigold 2000 ppm, spearmint, basil, quyssum (3000 ppm) completely inhibit all the test fungi. Caraway was inhibitory at 2000 ppm against A. flavus, A. parasiticus and 3000 ppm against A. ochraceaus and F. moniliforme. A. flavus, A. ochraceus, A. parasiticus and F. moniliforme were completely inhibited by anise 500 ppm. However, chamomile and hazanbul at all concentrations were partially effective against the test toxigenic fungi. The results indicate that the test toxigenic fungi are sensitive to the 12 essential oils, and particularly sensitive to thyme and cinnamon. The results also showed that the essential oils of thyme, cinnamon, anise and spearmint have more effect on fungal development and subsequent mycotoxin production in wheat grains. The extent of inhibition of fungal growth and mycotoxin production was dependent on the concentration of essential oils used.


Effect of oil extracted from some medicinal plants on different mycotoxigenic fungi.
Food Chem Toxicl 2002 Nov;40(110:1669-75
Soliman KM, Badeaa RI, Food Technology and Dairy Departments, National Research Center, Dokki, Cairo, Egypt.



Peppermint – safety assessment
Approved by the Food and Drug Administration in the United States, peppermint is deemed safe for all humans that are not found allergic to the plant or oil.


Isolated clinical cases of irritation and/or sensitization to Peppermint Oil and/or its constituents have been reported, but Peppermint Oil (8%) was not a sensitizer when tested using a maximization protocol. It was expected that dermal absorption of Peppermint Oil would be rapid, following that of menthol, a major component, but in no case would be greater than absorption through the gastrointestinal tract. Because of the toxicity of pulegone, the safe concentration of this constituent was limited to 1%. This concentration was achievable both by controlling the time of harvest and processing technique. There is evidence that menthol can enhance penetration of other agents. Formulators were cautioned that this enhanced penetration can affect the use of other ingredients whose safety assessment was based on their lack of absorption. With the limitation that the concentration of pulegone in these ingredients should not exceed 1%, it was concluded that Mentha Piperita (Peppermint) Oil, Mentha Piperita (Peppermint) Extract, Mentha Piperita (Peppermint) Leaves, Mentha Piperita (Peppermint) Water are safe as used in cosmetic formulations.


Final report on the safety assessment of Mentha Piperita (Peppermint) Oil, Mentha Piperita (Peppermint) Leaf Extract, Mentha Piperita (Peppermint) Leaf, and Mentha Piperita (Peppermint) Leaf Water. Int. J. Toxicol. 2001;20 Suppl.3:61-73 Nair B.



Spearmint Oil and Allergic Reactions
This study talks about how spearmint is perfectly safe for everyday use in people without allergic reactions.


The present work reports the results of a multicentre study of toothpaste allergic contact cheilitis (TACC) conducted by GIRDCA (Gruppo Italiano Ricerca Dermatiti da Contatto e Ambientali). The study examined 54 patients with eczematous lesions on the lips, the possible cause of which was suspected to be the use of toothpastes. Patch tests were conducted with a standard series, a specially-targeted series (toothpaste cheilitis series, TCS), and with suspected toothpaste(s). A stop-restart test (SRT) was carried out with these, together with a use test to identify possible alternative products. The TCS produced 17 positive reactions in 13 patients, the most frequent being to spearmint oil. Of the 54 patients, 5 displayed positive reactions only to the TCS. The patch tests with toothpaste produced positive reactions in 11/32 patients, the SRT a positive response in 10/12 cases. The diagnosis of TACC was confirmed in 15/54 patients. Alternative products were identified for 5 patients. In conclusion, the allergens most frequently responsible for TACC were the flavourings, and the additional series proved to be useful in many cases (together with patch tests with toothpastes and the SRT) for correct diagnosis and to initiate effective prevention.


Multicentre study of allergic contact cheilitis from toothpastes. Contact Dermatitis 2000 Oct;43(4):216-22 Francalanci S, Sertoli A, Giorgini S, Pigatto P, Santucci B, Valsecchi R, II Dermatologic Clinic, Florence University Institute of Dermatology, Italy.



Almond oils
This study measures the excellent qualities almond oils have against organisms and bacteria. We’ve found that almond oils create a great base for which peppermint and spearmint can attack bacteria most effectively.


The antimicrobial activity of plant oils and extracts has been recognized for many years. However, few investigations have compared large numbers of oils and extracts using methods that are directly comparable. In the present study, 52 plant oils and extracts were investigated for activity against Acinetobacter baumanii, Aeromonas veronii biogroup sobria, Candida albicans, Enterococcus faecalis, Escherichia col, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella enterica subsp. enterica serotype typhimurium, Serratia marcescens and Staphylococcus aureus, using an agar dilution method. Lemongrass, oregano and bay inhibited all organisms at concentrations of 2.0% (v/v). Six oils did not inhibit any organisms at the highest concentration, which was 2.0% (v/v) oil for apricot kernel, evening primrose, macadamia, pumpkin, sage and sweet almond. Variable activity was recorded for the remaining oils. Twenty of the plant oils and extracts were investigated, using a broth microdilution method, for activity against C. albicans, Staph. aureus and E. coli. The lowest minimum inhibitory concentrations were 0.03% (v/v) thyme oil against C. albicans and E. coli and 0.008% (v/v) vetiver oil against Staph. aureus. These results support the notion that plant essential oils and extracts may have a role as pharmaceuticals and preservatives.


Antimicrobial activity of essential oils and other plant extracts. J Appl Microbiol 1999 Jun;86(6):985-90 Hammer KA, Carson CF, Riley TV. Department of Microbiology, The University of Western Australia, Nedlands, Western Australia.